In vitro, pvl induces polymorphonuclear cell death by necrosis or by apoptosis, depending on the pvl concentration.
19+ Panton Valentine Leukocidin Background. It tells you what it is, what causes it, the symptoms, what can be done about it and where you can find more information. What are the aims of this leaflet?
(PDF) Panton-Valentine Leukocidin-positive methicillin ... from i1.rgstatic.net
26 pvl has been associated with severe inflammatory lesions, presumably through the activation of granulocytes. These may be meticillin susceptible (mssa) or mrsa strains. The aim of this study was to determine the prevalence of the pv1 , meca , and nuc genes in staphylococcus aureus isolates obtained from anterior nares and superficial infection sites of skin in a slum population of west bengal, india.
These strains are responsible for primary skin infections and necrotizing pneumonia.
Elizur a, orscheln rc, ferkol tw, et al; In vitro, pvl induces polymorphonuclear cell death by necrosis or by apoptosis, depending on the pvl concentration. Structurally similar to γ haemolysin, this leukocidin comprises two subunits (f and s) that together are leukocidal and dermonecrotic. Aureus which have succeeded in invading human tissue were found capable of producing in vitro considerable amounts.
